Impact of adverse childhood experiences on the symptom severity of different mental disorders: a cross-diagnostic study
不良童年经历对不同精神障碍症状严重程度的影响：一项交叉诊断研究
さまざまな精神障害の症状の重症度に 対する逆境的小児期の経験の影響：相互診断研究
다양한 정신 장애의 증상 중증도에 대한 불리한 아동기 경험의 영향: 교차 진단 연구
Impacto de las experiencias infantiles adversas en la gravedad de los síntomas de diferentes trastornos mentales: un estudio de diagnóstico cruzado
Impact des expériences négatives de l'enfance sur la gravité des symptômes de différents troubles mentaux : une étude de diagnostic croisé
Текст научной работы на тему «Влияние неблагоприятного детского опыта на тяжесть симптомов различных психических расстройств: перекрестное диагностическое исследование»
Wenjie Gu 顾文洁, Qing Zhao 赵青, Chengmei Yuan 苑成梅 , Zhenghui Yi 易正辉, Min Zhao 赵敏, Zhen Wang 王振
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
中国 上海 上海交通大学医学院 上海市精神卫生中心
Adverse childhood experiences have a significant impact on different mental disorders.
Objective
To compare differences in adverse childhood experiences among those with different mental disorders and their relationships in a cross-disorder manner.
Methods
The study included 1513 individuals aged ≥18 years : 339 patients with substance use disorders, 125 patients with schizophrenia, 342 patients with depression, 136 patients with bipolar disorder, 431 patients with obsessive-compulsive disorder (OCD), and 140 healthy controls. The Early Trauma Inventory Self Report-Short Form was used to investigate childhood traumatic experiences, and the Addiction Severity Index, Positive and Negative Syndrome Scale, Hamilton Depression Scale, Young Mania Rating Scale, and Yale-Brown Obsessive-Compulsive Scale were used to assess mental disorder severity. Correlation and multivariate logistic regression were analysed between adverse childhood experiences and clinical features.
Results
Levels of adverse childhood experiences were significantly different among different mental disorders. Moreover, 25.8% of patients with substance use disorders reported childhood trauma, which was significantly higher than found in the other four psychiatric disorder groups. Emotional abuse scores were positively correlated with disease severity: the higher the total trauma score, the more severe the mental disorder.
Conclusions
Adverse childhood experiences are a common phenomenon in those with mental disorders, and the level of trauma affects mental disorder severity. Emotional abuse is closely related to many mental disorders. The incidence or severity of mental disorders can be reduced in the future by reducing the incidence of adverse childhood experiences or by timely intervention in childhood trauma.
